Huntington's Disease

Huntington's Disease (HD) results from genetically programmed degeneration of brain cells, called neurons, in certain areas of the brain. This degeneration causes uncontrolled movements, loss of intellectual faculties, and emotional disturbance. HD is a familial disease, passed from parent to child through a mutation in the normal gene. Each child of an HD parent has a 50-50 chance of inheriting the HD gene. If a child does not inherit the HD gene, he or she will not develop the disease and cannot pass it to subsequent generations . A person who inherits the HD gene will sooner or later develop the disease. Whether one child inherits the gene has no bearing on whether others will or will not inherit the gene. Some early symptoms of HD are mood swings, depression, irritability or trouble driving, learning new things, remembering a fact, or making a decision. As the disease progresses, concentration on intellectual tasks becomes increasingly difficult and the patient may have difficulty feeding himself or herself and swallowing. The rate of disease progression and the age of onset vary from person to person. A genetic test, coupled with a complete medical history and neuroloical and laboratory tests, helps physicians diagnose HD. Presymptomic testing is available for individuals who are at risk for carrying the HD gene. In 1 to 3 percent of individuals with HD, no family history of HD can be found.

At this time, there is no way to stop or reverse the course of HD.

My grandmother Shirley had HD and passed away due to the disease before I was born. My uncle Randy, my mother's older brother, is currently living with HD in a "care home". He's going down hill fast. Like stated above, there is a test you can take to find out if you have the active gene. It's kind of like a death sentence, right? I mean, you take the test, find out that you have it and then what? You just sit around and wati? Fuck that! My mother doesn't have the gene, so that's a plus for me, right? Either way, I've decided that I'm not going to bother with the test.